| Game |
| Result | Moves |
Year | Event/Locale | Opening |
| 1. Gelfand vs Caruana |
 | ½-½ | 34 | 2009 | Biel International Chess Festival | E32 Nimzo-Indian, Classical |
| 2. Nakamura vs Caruana |
| ½-½ | 65 | 2014 | FIDE Grand Prix Tashkent | E32 Nimzo-Indian, Classical |
| 3. Aronian vs Caruana |
| 0-1 | 40 | 2015 | GRENKE Chess Classic | E32 Nimzo-Indian, Classical |
| 4. Navara vs Caruana |
 | 1-0 | 55 | 2016 | Tata Steel Masters | E32 Nimzo-Indian, Classical |
| 5. B Finegold vs Caruana |
| 0-1 | 46 | 2017 | PRO Chess League (Knock-Out) | E32 Nimzo-Indian, Classical |
| 6. Shankland vs Caruana |
| ½-½ | 37 | 2017 | United States Championship | E32 Nimzo-Indian, Classical |
| 7. Nakamura vs Caruana |
| ½-½ | 43 | 2017 | London Chess Classic | E32 Nimzo-Indian, Classical |
| 8. Mamedyarov vs Caruana |
| ½-½ | 47 | 2018 | Pro Chess League | E32 Nimzo-Indian, Classical |
| 9. Mamedyarov vs Caruana |
| ½-½ | 63 | 2018 | Your Next Move (Blitz) | E32 Nimzo-Indian, Classical |
| 10. Mamedyarov vs Caruana |
| ½-½ | 30 | 2018 | Grand Chess Tour Paris (Rapid) | E32 Nimzo-Indian, Classical |
| 11. Mamedyarov vs Caruana |
| 1-0 | 43 | 2018 | St. Louis Rapid & Blitz (Blitz) | E32 Nimzo-Indian, Classical |
| 12. Mamedyarov vs Caruana |
| ½-½ | 37 | 2019 | Sinquefield Cup | E32 Nimzo-Indian, Classical |
| 13. Mamedyarov vs Caruana |
| 1-0 | 34 | 2019 | GCT Bucharest Rapid & Blitz | E32 Nimzo-Indian, Classical |
| 14. Giri vs Caruana |
| ½-½ | 63 | 2020 | Tata Steel Masters | E32 Nimzo-Indian, Classical |
| 15. Vitiugov vs Caruana |
| ½-½ | 23 | 2020 | Tata Steel Masters | E32 Nimzo-Indian, Classical |
| 16. Carlsen vs Caruana |
| 1-0 | 51 | 2020 | Norway Chess | E32 Nimzo-Indian, Classical |
| 17. So vs Caruana |
| ½-½ | 26 | 2021 | United States Championship | E32 Nimzo-Indian, Classical |
| 18. T Gareyev vs Caruana |
| ½-½ | 47 | 2021 | World Rapid Championship | E32 Nimzo-Indian, Classical |
| 19. Harikrishna vs Caruana |
| ½-½ | 18 | 2022 | Chennai Olympiad | E32 Nimzo-Indian, Classical |
| 20. Niemann vs Caruana |
| 0-1 | 80 | 2022 | U.S. Championship | E32 Nimzo-Indian, Classical |
| 21. Indjic vs Caruana |
| 0-1 | 31 | 2022 | World Blitz Championship | E32 Nimzo-Indian, Classical |
| 22. So vs Caruana |
| ½-½ | 31 | 2023 | United States Championship | E32 Nimzo-Indian, Classical |
| 23. So vs Caruana |
| ½-½ | 31 | 2023 | CCT Final Prelims | E32 Nimzo-Indian, Classical |
| 24. So vs Caruana |
| ½-½ | 26 | 2024 | World Blitz Championship | E32 Nimzo-Indian, Classical |
Kibitzing
